Dishonored 2 Safe Combinations

Safe combinations in Dishonored 2 will allow you to unlock various safes across Karnaca. They’ll sometimes contain runes, other times gold or bonecharms, but every one you open will have something valuable inside.
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It’s worth opening up every one, but the number sequences used to open them are often well hidden. In this guide, we’re going to show you all Dishonored 2 safe combinations, where to find them, as well as locations of the strongboxes they open and the loot you’ll find inside.

Most of the combinations are randomized, so they’ll end up being different for everyone. This is why we won’t list the combinations we got, but the locations where we found them instead. This way, you’ll have to visit the place to get the number sequence, but it will definitely work. There are several safes in the game that are unlocked, as well. These contain nothing of importance (a little money, at best) and can be opened as soon as you find them, so we won’t be listing them here. The ones we list are all locked, and contain something valuable, like a rune, bonecharm or blueprint.

Mission 1: A Long Day In Dunwall

Name: Steel Monitor Safe

Safe location: After you leave Dunwall tower made the first kill from the air and have those 3 guys getting orders from a guard. Hold on to the left. Get inside the house with a large “For Rent” sign. Kill one guard and there’s a safe in the room.
Combination location: Behind the painting on the right.
Rewards: 2x Silver Ingot, Pistol, 2x Pistol bullets
Thanks Xantronix for providing all information..

Click here to watch the video walkthrough for Mission 1: Steel Monitor Safe Combination

Mission 2: Edge of The World

Name: Winslow safe

Safe location: In the store across the road from Addermire station, in the southwestern corner of the map. You’ll find it on the ground floor, near the back. You can enter the store from a back alley, if you want to avoid being seen.
Combination location: In the cash register, in the same shop.
Rewards: Bone charm, Gold ingot, Silver ingot x2, Pistol, Pistol bullets

Click here to watch the video walkthrough for Mission 2: Winslow Safe Combination

Name: Overseer Office Safe

Safe location: In the Overseer Offices, across the canal from the building with the giant Seized! banner. It’s in the Vice Overseer’s office. The building is teeming with religious fanatics, so make sure you either stay out of sight, or have enough firepower to deal with the inquisition.
Combination location: Written on a piece of paper, left on the desk in the darkened room next to the large office (on the same floor where the safe is).
Rewards: Rune, 3x Silver ingot, Raw whalebone

Click here to watch the video walkthrough for Mission 2: Overseer Office Safe Combination

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